Outsourcing Abuse Liability Testing
March 7, 2009 8:35 am Drug DependenceI’m looking for input regarding the outsourcing of abuse liability testing. I’m curious as to which models are being used and which contract organizations have offerings and experience in this area.




March 8th, 2009 at 8:34 pm
Dear Ptaranti,
You may contact Porsolt & Partners company which is a CRO specialised in safety pharmacology and I believe they have models to assess drug abuse liability.
Good luck
Dr. M. R. Srinivasan
April 2nd, 2009 at 9:37 am
Dear Ptaranti,
FYI CERB is also a CRO specialised in safety pharmacology and we have such models available .
Regards
Eric
April 6th, 2009 at 12:59 pm
Dear Ptaranti,
So far we have successfully worked with MPI, Porsolt and MediMod.
Kind regards,
Greet
April 23rd, 2009 at 5:00 am
Definitely Porsolt…..
May 12th, 2009 at 6:30 am
MPI Research conducts all three assays: dependence liability, drug discrimination and self-administration studies in both rats and monkeys fully GLP compliant. Equipment, protocols, SOPs, and method validations are fully GLP compliant.
Porsolt can also run these but they are not GLP compliant. The behavioral studies are usually outsourced to Dr. Charles France at UT in the USA.